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A meta-Assessment of 14 reports showed the specificity of an elevated troponin over the 99th percentile was substantially decreased in sufferers with CKD. It is critical to know In case the troponins are trending over time in these individuals.[seventy three] The troponin amounts in sufferers with CKD tend to be regular, so a rise and fall on the troponin could well be more indicative of a cardiac reason behind the elevated troponin.

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Autoantibodies also have the possible to lead to interference in troponin immunometric assay methods. Wrong-positive or Phony-damaging values may perhaps come up, based upon whether the autoantibody-analyte intricate partitions into the absolutely free or the certain analyte portion.

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